Unusual Progression of Renal Cell Carcinoma with Carcinomatosis Peritoneii and Krukenberg Tumor and Alopecia with Sunitinib Therapy in a Young Female

    February 2018 in “ World journal of surgical oncology ”
    Manoj Pandey, Ratha Mahendran, Manish Shukla
    TLDR A young woman with kidney cancer experienced rare hair loss from a cancer drug and unusual cancer spread, suggesting early drug treatment might reduce spread and prolong survival.
    The document described a rare case of a 22-year-old female with renal cell carcinoma that progressed unusually to include carcinomatosis peritoneii and a Krukenberg tumor, and who developed alopecia as a side effect of sunitinib therapy. The patient's alopecia was attributed to sunitinib after ruling out other causes. The case underscored the complexity of managing side effects in targeted cancer therapies and suggested that adjuvant tyrosine kinase inhibitors post-tumor resection might reduce metastasis and improve progression-free survival. Despite switching to sorafenib, the patient eventually died of progressive disease.
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