An Unusual Case of Increased Hair Pigmentation in Previously Grey-White Hair

The document reports an unusual case of a 73-year-old male who experienced a change in hair color from grey-white to dark brown following treatment for late onset erythrodermic eczema. The patient's eczema was initially treated with ciclosporin, which was discontinued due to hypertension and lack of benefit, and then with azathioprine and prednisolone, along with narrowband UVB phototherapy. While the eczema improved, an unexpected side effect was the darkening of his hair, which had been grey-white for 30 years. The exact mechanism behind the increased hair pigmentation is unclear, but it is suggested that the combination of treatments for eczema may have contributed to this effect. There were no previous reports of hair darkening associated with azathioprine, prednisolone, or UVB therapy.