Ultrasound Depolymerization and Characterization of Poly- and Oligosaccharides from the Red Alga Solieria Chordalis

The study focused on the depolymerization and characterization of polysaccharides from the red alga Solieria chordalis, using ultrasound and hydrogen peroxide to produce low-molecular-weight carrageenans. Ultrasound was particularly effective in preserving sulfate content while reducing molecular weight, achieving fractions with enhanced bioactivity. These fractions showed no cytotoxic effects and even increased human dermal fibroblast proliferation by up to 56.10% at certain concentrations, indicating potential applications in cosmetics and biomedicine. The research highlights ultrasound as a promising green method for producing bioactive polysaccharides with potential human applications.