Efficacy and Safety of Triamcinolone Hexacetonide Compared to Platelet-Rich Plasma and Minoxidil in the Treatment of Alopecia Areata

    February 2025 in “ Revista Eletrônica Acervo Saúde ”
    Larissa Souza de Jesus, João Victor Oinhos de Oliveira, Arão Belitardo Oliveira, J. Fernandes, Ana Carolina Cola, Luana de Melo Simmer, Larissy da Silva Maciel, Taíssa Louzada Sandrini, Edilberto Duarte Vieira Pimentel, Priscila de Jesus Santana
    From the encyclopedia
    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Image
    Studysummary This integrative review found that triamcinolone hexacetonide remains the primary treatment for mild to moderate alopecia areata but noted its significant side effects with prolonged use, while emerging therapies like PRP and minoxidil offer promising alternative benefits with fewer risks. Our plain-language summary of this paper — not a Tressless recommendation.
    This integrative review evaluates the efficacy and safety of triamcinolone hexacetonide for treating alopecia areata, comparing it with platelet-rich plasma (PRP) and minoxidil. The review analyzed 243 articles from PubMed Central, highlighting that triamcinolone hexacetonide remains a first-line treatment despite its limited availability in Brazil. PRP, especially when combined with topical minoxidil, is presented as an effective alternative. While triamcinolone is effective for mild to moderate alopecia areata, it has significant side effects with prolonged use. Emerging therapies like PRP and minoxidil offer promising alternatives with fewer risks and comparable results.
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