A Case of Treatment-Resistant Erosive Pustular Dermatosis of the Scalp

    January 2025 in “ SAGE Open Medical Case Reports
    Zahra Rehan, Tracey Brown‐Maher
    TLDR Combination therapy may be more effective for difficult-to-treat scalp conditions.
    This case report discusses a 72-year-old male with treatment-resistant erosive pustular dermatosis of the scalp (EPDS), a rare inflammatory condition that can lead to scarring alopecia. Despite trying multiple treatments, including corticosteroids, antibiotics, calcineurin inhibitors, and isotretinoin, the patient's condition showed minimal improvement. The report suggests that combination therapy may be more effective than monotherapy for refractory EPDS. The case highlights the challenges in diagnosing and managing EPDS, emphasizing the importance of considering combination therapies and the potential need for biopsy in non-responsive cases.
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