Transplants from balding and hairy androgenetic alopecia scalp regrow hair comparably well on immunodeficient mice
May 2003
in “
Journal of The American Academy of Dermatology
”
TLDR Hair from balding and non-balding areas regrows similarly on mice.
A study from 20 years ago found that hair follicles from both balding and non-balding areas of the scalp have the potential to regenerate quickly once removed from the human scalp and transplanted onto immunodeficient mice. The study suggests that hair follicles from balding scalps can still be used for hair transplantation. The study also found that the mouse environment is less than optimal for the growth of follicles originating from hairy scalp, with the rate of increase in length of these hairs appearing to be close to normal or only slightly diminished, but the mean diameter is markedly reduced.
View this study on jaad.org →
Discuss this study in the Community →
Cited in this study
6 / resultsresearch Possible mechanisms of miniaturization during androgenetic alopecia or pattern hair loss
Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
research Alopecia: unapproved treatments or indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Finasteride in the treatment of men with androgenetic alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
research Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp
Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
research Reduced Linear Hair Growth Rates of Vellus and of Terminal Hairs Produced by Human Balding Scalp Grafted onto Nude Mice
Balding scalps slow down hair growth.
Related
6 / resultsresearch Hair Loss (Alopecia or Baldness)
Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
research Morphological and Morphometric Study of the Androgenetic Alopecic Scalp Using Two- and Three-Dimensional Analysis Comparing Regional Differences
The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
research Use of Micrografts and Minigrafts in Hair Restoration
Micrografts and minigrafts for hair restoration provide high patient satisfaction and can cover large areas of hair loss, including sideburns, eyebrows, and beards.
research Transplants from balding and hairy androgenetic alopecia scalp regrow hair comparably well on immunodeficient mice
Hair from balding and non-balding areas regrows similarly on mice.
research Hair anatomy for the clinician
Understanding hair follicle anatomy helps diagnose hair disorders.
research Drugs Affecting Hair Growth
Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.