Transplanted Hair Follicle Stem Cells Migrate to the Penumbra and Express Neural Markers in a Rat Model of Cerebral Ischaemia/Reperfusion

    Xuemei Zhang, Hao Tang, Senlin Mao, Bing Li, Yinglian Zhou, Hui Yue, Duo Wang, Yifei Wang, Jin Fu
    TLDR Hair follicle stem cells may help treat strokes by improving brain recovery.
    The study investigated the potential of hair follicle stem cells (HFSCs) in treating ischaemic stroke using a rat model. HFSCs were intravenously administered to rats with induced middle cerebral artery ischaemia/reperfusion. The results showed that HFSCs migrated to the penumbra, expressed neuron-specific markers, reduced infarct volume, and promoted neurological recovery. These findings suggested that HFSC transplantation had therapeutic potential for ischaemic stroke and warranted further investigation for clinical development.
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