Transplanted Hair Follicle Stem Cells Migrate to the Penumbra and Express Neural Markers in a Rat Model of Cerebral Ischaemia/Reperfusion

August 2020 in “ Research Square (Research Square) ”

Xuemei Zhang, Hao Tang, Senlin Mao, Bing Li, Yinglian Zhou, Hui Yue, Duo Wang, Yifei Wang, Jin Fu

TLDR Hair follicle stem cells may help treat strokes.

The study investigated the potential of hair follicle stem cells (HFSCs) in treating ischaemic stroke using a rat model. Researchers found that intravenously administered HFSCs migrated to the penumbra, expressed neuron-specific markers, reduced infarct volume, and promoted neurological recovery. These findings suggested that HFSC transplantation had therapeutic potential for ischaemic stroke, warranting further investigation for clinical development.

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research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives

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