Topical Minoxidil Dose-Response Effect in Alopecia Areata

    February 1986 in “Archives of Dermatology
    Virginia C. Fiedler-Weiss, Dennis P. West, Cunera Buys, Jean A. Rumsfield
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    TLDR Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.
    The study found that a 5% topical minoxidil solution was significantly more effective than a 1% solution in treating severe alopecia areata, with 85% of patients experiencing hair regrowth after 48 to 60 weeks of treatment. The study suggests that exploring modifications in dosing and delivery systems may enhance therapeutic efficacy.
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