Treatment of Central Centrifugal Cicatricial Alopecia with Topical Metformin 10% Cream: Case Report and Literature Review

    Bárbara Vieira Granja, Pedro Matos, Gilberto Pires da Rosa, Jorge Pinheiro, Filomena Azevedo, Ana Filipa Pedrosa
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    TLDR Topical metformin 10% cream may help treat central centrifugal cicatricial alopecia.
    The document reports a case study and literature review on the use of topical metformin 10% cream for treating central centrifugal cicatricial alopecia (CCCA). The authors present a case where a patient with CCCA showed significant improvement after using the topical metformin treatment. This case adds to the limited but growing body of evidence suggesting that metformin, known for its anti-fibrotic properties, may be effective in treating CCCA. The review also highlights previous studies and cases that support the potential of metformin in promoting hair regrowth in patients with this condition. No conflicts of interest or funding sources were reported.
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