learn Metformin
diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
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a topical anti-androgen with less systemic involvement
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powerful topical and oral anti-androgen used mostly by women
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a novel topical treatment that inhibits DHT on androgen receptors
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
Research
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research Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin
Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.
research Topical Metformin in Dermatology: A Narrative Review of Efficacy and Formulation Approaches
Topical metformin shows promise for treating skin conditions like acne and psoriasis.
research A Systematic Review on Clinical Evidence for Topical Metformin: Old Medication With New Application
Topical metformin shows promise for dental and skin treatments, including periodontitis, hair regrowth, wound healing, and acne.
research Treatment of Central Centrifugal Cicatricial Alopecia with Topical Metformin 10% Cream: Case Report and Literature Review
Topical metformin 10% cream may help treat central centrifugal cicatricial alopecia.
research Topical Metformin as a Novel Therapy for Alopecia Areata Due to Its Immunologic Effects
Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
Community Join
5 / 1000+ resultscommunity Topical Metformin for Hair Transplant donor area skin/hair regeneration?
Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.
community Can I make a DIY Topical metformin?
The conversation is about using DIY topical metformin for hair loss. A user tried it without success, and it was not combined with microneedling.
community TCA 35% chemical peel, don't try this shit at home.
The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Topical rapamycin, metformin, a-kg grow hair
The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.