The Role of Topical Finasteride in Hair Loss Management: Current Evidence and Future Perspectives

The document reviews the potential benefits of topical finasteride (FIN) for treating male pattern hair loss by inhibiting DHT, which shrinks hair follicles. It contrasts the reduced systemic side effects of topical FIN, such as decreased libido and erectile dysfunction, with those of oral FIN. However, it notes the lack of established efficacy and safety due to limited clinical trials and inconsistent use protocols. The document calls for future research to standardize application methods, assess long-term effects, and compare topical FIN to other treatments. It also mentions a phase III randomized controlled clinical trial and acknowledges support from Prince Sattam bin Abdulaziz University, with no competing interests declared.