TLDR Topical finasteride effectively and safely improves hair growth in men with androgenetic alopecia.
The study evaluated the effectiveness and safety of topical finasteride 0.25% over 52 weeks in 146 men with androgenetic alopecia (AGA). Results showed a significant increase in target area hair count (TAHC) at both the vertex (+22.7 hairs/cm²) and frontotemporal regions (+32.3 hairs/cm²), along with improvements in hair width and the terminal-to-vellus hair ratio. The mean Male Hair Growth Questionnaire (MHGQ) score was 14.7, and the Physician Global Assessment (PGA) was +1.9, indicating positive outcomes. Mild, transient local irritation was reported in 6.2% of patients, with no systemic adverse effects. The findings suggest that topical finasteride is an effective and safe long-term treatment for male AGA, particularly in the frontotemporal regions.
The user is considering using topicalfinasteride for thinning hair around the middle part, vertex, and crown, and is unsure if the whole scalp is thinning. Another user suggests oral finasteride is more effective than topical, and recommends consulting a dermatologist for proper treatment.
The user experienced significant hair improvement after one year using topicalfinasteride and minoxidil, combined with a hair transplant at the front. They switched from oral to topicalfinasteride due to side effects and are satisfied with the results, especially at the temples.
Topicalfinasteride (P-3074) can inhibit scalp DHT by up to 70%, with some users experiencing systemic absorption similar to oral use. Users discuss varying application frequencies and concentrations, with some noticing side effects when overused.
The user was prescribed 0.3% topicalfinasteride with 5% minoxidil for use on the temples twice daily, while continuing minoxidil on the full scalp. Replies suggested using the treatment once daily and questioned the logic of treating only the temples, with one suggesting dilution for use across the entire scalp.
Topical dutasteride, particularly at 0.05%, shows greater hair density improvement than oral finasteride over 24 weeks, though hair thickness gains are similar. Some users report side effects with topical treatments, but others find them effective for maintaining hair without significant systemic absorption.
The user switched from oral to topicalfinasteride with minoxidil after a hair transplant and is experiencing increased hair growth in unexpected areas like eyebrows and sideburns. They are seeking feedback from others with similar experiences.
