Topical cetirizine and oral vitamin D: a valid treatment for hypotrichosis caused by ectodermal dysplasia
TLDR Using cetirizine on the skin and taking vitamin D can help increase hair growth in children with hair loss from ectodermal dysplasia.
In a study from 2016, three girls aged 9, 5, and 6 with congenital hypotrichosis due to ectodermal dysplasia were treated with a combination of topical cetirizine solution (2 mL once daily) and oral vitamin D supplementation (1000 IU daily). After 6 months of treatment, all patients experienced an increase in scalp hair density, with vellus hair being replaced by terminal hair. The hair regrowth was assessed both clinically and through trichoscopy. The study concluded that the combination of topical cetirizine and oral vitamin D could be an effective treatment for congenital hypotrichosis associated with ectodermal dysplasia.
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