Employment of Current Results of Tissue Engineering in the Development of Skin Substitutes

    January 2012 in “ PubMed ”
    Jana Dragúńová, Ján Koller, Cucorová
    TLDR Tissue engineering advancements are improving skin substitutes for better burn treatment.
    The document reviewed the advancements in tissue engineering for developing skin substitutes, particularly for treating extensive burns. It highlighted the potential of biosynthetic and combined skin substitutes to mimic the structure and functions of normal skin. Existing substitutes included cultured keratinocytes, composites, acellular matrices, and matrices based on biological substances like collagen and hyaluronic acid. The research aimed to create fully functional skin substitutes capable of revascularization, reinnervation, and replacing skin appendages such as hair follicles and sebaceous glands. Achieving this required collaboration across various scientific disciplines, and recent advances were promising for future developments.
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