The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation
July 1999
in “
American Journal Of Pathology
”
Research cited in this study
16 / 16 results
research Principles of Hair Cycle Control
Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
research A Missense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia in a Family of Irish Travellers
research Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans
The hr gene is crucial for skin and hair health, with mutations causing hair disorders.
research Towards Defining the Pathogenesis of the Hairless Phenotype
research Alopecia Universalis Associated with a Mutation in the Human hairless Gene
The study investigated a kindred with a rare, recessively inherited type of alopecia universalis to identify the genetic basis of this condition. Through homozygosity mapping, researchers established linkage in a 6-centimorgan interval on chromosome 8p12, with a significant logarithm of the odds score of 6.19. They identified a missense mutation in the human homolog of the murine hairless gene within this interval. The human hairless gene encodes a putative single zinc finger transcription factor protein, which is expressed in the brain and skin, suggesting its role in the development of alopecia universalis.
research Immunohistochemical analysis of tissue remodelling during the anagen—catagen transition of the human hair follicle
research Immunohistochemical analysis of tissue remodelling during the anagen-catagen transition of the human hair follicle
research Keratin 17 Gene Expression during the Murine Hair Cycle
research Dermal-Epidermal Interactions in Hair Follicle Development and Maintenance
Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
research A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A
Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.
research Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis
Specific proteins and molecules play key roles in the development of human hair follicles.
research A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.
research Outer root sheath keratinization in anagen and catagen of the mammalian hair follicle. A seventh distinct type of keratinization in the hair follicle: trichilemmal keratinization.
research Morphogenesis of the hair follicle during catagen
research Growth of the Hair
Hair growth is cyclic and influenced mainly by local factors.