TLDR The keratin naming system was updated to include 54 genes, especially for hair-related keratins.
The document outlined a revision of the keratin nomenclature due to the identification of 54 keratin genes, up from the original 19. This revision aimed to establish a logical numbering system, particularly for keratins in the hair follicle, while retaining the original names for keratins K1–K19. Changes mainly affected hair shaft and inner root sheath keratins. The revised system was intended for future publications to reflect the diversity of keratins, which vary by cell type and differentiation state, emphasizing their significance in dermatology research and the potential for discovering new keratins in other mammals.
93 citations
,
July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
92 citations
,
February 2005 in “Journal of Investigative Dermatology” 108 citations
,
October 2003 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin makes hair follicles stronger.
130 citations
,
April 2003 in “Journal of Investigative Dermatology” 272 citations
,
September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
41 citations
,
January 2001 in “Journal of Investigative Dermatology” 235 citations
,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
238 citations
,
May 1989 in “Journal of Investigative Dermatology”