The calcium-binding protein calretinin is a marker of the companion cell layer of the human hair follicle

June 2005 in “ British Journal of Dermatology ”

Enrique Poblet, F. Jiménez, Carlos de Cabo, Ana I. Prieto-Martín, Ricardo Sánchez‐Prieto

TLDR Calretinin identifies the companion cell layer in human hair follicles.

The study demonstrated that calretinin, a calcium-binding protein, served as a specific marker for the companion cell layer of the human hair follicle, distinguishing it from other cells of the outer root sheath (ORS) both morphologically and immunohistochemically. This finding contributed to a deeper understanding of the unique characteristics of the companion layer within the hair follicle structure.

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