Effect of Exogenous Testosterone, Finasteride, and Castration on Serum Level of Thyroxin

    August 2013 in “ PubMed
    Fatemeh Zarei, Namdar Yousofvand, Mozafar Khazaei, Ali Ghanbari
    TLDR Testosterone changes reduce thyroxin levels in rats.
    The study investigated the effects of testosterone, finasteride, and castration on serum thyroxin (T4) levels and body metrics in male rats. It involved 32 rats divided into four groups: control, castration, finasteride, and testosterone. After 35 days, results showed that body weight increased in castrated rats and decreased in those given testosterone, with no significant change in the finasteride group. Prostate weight increased with testosterone and decreased with castration and finasteride, while testis weight remained unchanged across groups. Serum T4 levels decreased in all experimental groups, indicating that both high and low testosterone levels reduced T4 in a time-dependent manner.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 1000+ results

      community Natural finasteride for male deers

      in Satire  241 upvotes 1 week ago
      The conversation humorously discusses hair loss treatments, including minoxidil and finasteride, with a satirical suggestion of using fence castration as a natural finasteride for male deer. Participants joke about the side effects and effectiveness of these treatments.

      community 8 months on 5mg fin daily, 5% min twice daily, and hrt(mtf). Thought my hair was unrecoverable before but now I’m so happy.

      in Transgender  1898 upvotes 2 years ago
      A user named "LordGeek101" shared their positive experience with hair regrowth after using 5mg of finasteride daily, 5% minoxidil twice daily, and hormone replacement therapy (HRT) for 8 months. The user is transgender (MTF) and mentioned that the larger dose of finasteride was recommended by their doctor for better chances of hair revival.

      community My story/timeline/positive experience with Finasteride

       6 upvotes 12 years ago
      A 26-year-old male experienced positive results using 1mg Finasteride daily and 2% ketoconazole shampoo for hair loss, with reduced shedding and scalp itch. He reported no significant side effects and recommends early treatment for those in the initial stages of hair loss.

      community Can we stop fear mongering with finasteride

      in Finasteride/Dutasteride  285 upvotes 1 month ago
      Finasteride is effective for hair loss but can cause sexual dysfunction and mental health issues in some users, leading to a polarized debate on its risks. Some switch to alternatives like Dutasteride or topical treatments to avoid side effects.

    Similar Research

    5 / 1000+ results