TLDR Testosterone changes reduce thyroxin levels in rats.
The study investigated the effects of testosterone, finasteride, and castration on serum thyroxin (T4) levels and body metrics in male rats. It involved 32 rats divided into four groups: control, castration, finasteride, and testosterone. After 35 days, results showed that body weight increased in castrated rats and decreased in those given testosterone, with no significant change in the finasteride group. Prostate weight increased with testosterone and decreased with castration and finasteride, while testis weight remained unchanged across groups. Serum T4 levels decreased in all experimental groups, indicating that both high and low testosterone levels reduced T4 in a time-dependent manner.
4 citations
,
January 2013 in “PubMed” Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
18 citations
,
May 2002 in “BJUI” Finasteride doesn't change rat testicle weight or sperm production.
104 citations
,
October 1999 in “The Journal of Urology” Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.
24 citations
,
January 2011 in “Sexual Development” Intersex frogs have different brain gene activity related to sex and thyroid hormones.
January 2008 in “Pratique médicale & chirurgicale de l'animal de compagnie” Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.
52 citations
,
October 2004 in “Veterinary dermatology” Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
January 2007 in “Acta Veterinaria Brno” Trilostane treatment successfully restored hair growth in a dog with alopecia X.
January 2025 in “Applied Sciences” Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.