The Tabby (Ta), Tabby-C (Tac), And Tabby-J (TaJ) Mutations, Chromosome X
August 2020
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New to Epidermal Growth Factor? There is a guide in the encyclopedia. Read the guide → Studysummary This article discusses the impact of the tabby mutation on secondary vibrissae and hair follicle patterns in mice and reports no new clinical results.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The tabby (Ta), tabby-c (Tac), and tabby-J (TaJ) mutations in mice were studied for their effects on hair follicle development, specifically noting the absence of secondary follicles while primary vibrissae remained unaffected. These mutations were instrumental in exploring the role of epidermal growth factor, particularly in the context of hypohidrotic ectodermal dysplasia treatment. Additionally, they were utilized in genetic mapping on the X Chromosome, oogenesis studies, and as a double mutant with the gene for testicular feminization.
