SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair

September 2019 in “ Nature Communications ”

Qi Miao, Matthew C. Hill, Fengju Chen, Qianxing Mo, Amy T. Ku, Carlos Ramos, Elisabeth Sock, Véronique Lefebvre, Hoang Nguyen

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research Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties

143 citations , May 2017 in “Nature cell biology”

Wounded skin cells can revert to stem cells and help heal.

research Defining stem cell dynamics and migration during wound healing in mouse skin epidermis

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research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice

321 citations , March 2015 in “Nature”

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

research Tcf3 Promotes Cell Migration and Wound Repair Through Regulation of Lipocalin 2

55 citations , June 2014 in “Nature Communications”

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding

829 citations , May 2007 in “Nature”

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.