The Fabrication of Different Concentrations of Solid Lipid Nanoparticles of Finasteride
January 2011
in “
Hebei yixue
”
New to Finasteride? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that 0.1% concentrations of finasteride-loaded solid lipid nanoparticles showed high entrapment efficiency and homogeneity.
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The study explored the fabrication of solid lipid nanoparticles of finasteride at concentrations of 0.1%, 0.5%, and 1% using an improved emulsion evaporation-low temperature method. The 0.1% concentration demonstrated a homogeneous appearance with a particle size of 98.2±15.3 nm and an encapsulation rate of 96.3%. The conclusion was that the 0.1% concentration of solid lipid nanoparticles of finasteride showed high entrapment efficiency, homogeneity, and stability.