Circulating Sex Hormone Binding Globulin Levels Are Modified With Intensive Lifestyle Intervention, But Their Changes Did Not Independently Predict Diabetes Risk In The Diabetes Prevention Program

    December 2020 in “ BMJ Open Diabetes Research & Care ”
    Vanita R. Aroda, Christopher Christophi, Sharon L. Edelstein … Kieren J. Mather
    Studysummary This study found that while intensive lifestyle interventions were associated with favorable changes in SHBG levels due to reduced adiposity, these changes did not consistently predict diabetes risk reduction.
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    Research cited in this study 2

    1. Sex Hormone-Binding Globulin: An Important Biomarker for Predicting PCOS Risk - A Systematic Review and Meta-Analysis Systems Biology in Reproductive Medicine · 2017
    2. Sex Hormone–Binding Globulin and Risk of Hyperglycemia in Patients With Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011