Association of Serum IL-17A and IL-23 Levels With Alopecia Areata: A Cross-Sectional Comparative Study

    December 2025 in “ Cureus ”
    Md. Shihab Talukder, A.T.M. Asaduzzaman, Mohammad Abul Kalam Azad, Mohammad Jamal Uddin, Pranam Swapan Dash, Wasi Deen Ahmed
    TLDR Higher IL-17A and IL-23 levels are linked to alopecia areata severity and could help in tracking and treating the disease.
    Elevated levels of IL-17A are linked to the severity of alopecia areata (AA) and vary among different clinical subtypes, indicating its involvement in disease progression and phenotype differences. IL-23 is consistently elevated in AA, suggesting its potential as a biomarker for monitoring disease activity. These results enhance the understanding of cytokine dysregulation in AA and could guide the development of future treatments.
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