TLDR A method was found to select hair follicle stem cells, and beta-catenin helps them grow and change.
The study established a method for selecting hair follicle stem cells using their strong adherence to collagen, which increased the number of K19 positive cells by 1.6 times and clone forming efficiency by 3.5 times compared to unselected cells. The research demonstrated that #beta#-catenin played a role in regulating the proliferation and differentiation of these stem cells, as evidenced by increased nuclear expression of #beta#-catenin in quickly-adhered cells.
9 citations
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January 2016 in “International Journal of Medical Sciences” Increasing Wnt10b levels can help grow new hair follicles in mice.
January 2013 in “China Animal Husbandry & Veterinary Medicine” The best method to isolate and culture hair follicle stem cells in fine-wool sheep is a combination of two-step enzymatic digestion and mechanical separation.
January 2006 in “Chinese Journal of Dermatology” 92 citations
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December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
61 citations
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November 2004 in “Annals of the Academy of Medicine Singapore” Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.
87 citations
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February 2000 in “Journal of Investigative Dermatology”