Scarring Alopecia Associated With the Epidermal Growth Factor Receptor Inhibitor Erlotinib

April 2011 in “ Journal of the American Academy of Dermatology ”

Donna M. Hepper, Peggy A. Wu, Milan J. Anadkat

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Research cited in this study

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research Nonscarring Inflammatory Alopecia Associated With the Epidermal Growth Factor Receptor Inhibitor Gefitinib

57 citations , August 2006 in “Journal of the American Academy of Dermatology”

Gefitinib can cause hair loss without scarring.

research Genetically Null Mice Reveal a Central Role for Epidermal Growth Factor Receptor in the Differentiation of the Hair Follicle and Normal Hair Development

107 citations , June 1997 in “PubMed”

EGFR is essential for normal hair development and follicle differentiation.

research Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure.

252 citations , November 1995 in “The EMBO Journal”

Blocking EGFR in mice causes hair loss and skin changes.