Safety and Efficacy of Minoxidil Treatment in Scarring Alopecia: A Scoping Review

March 2024 in “ PubMed ”

Nathalie Ly, Erin M McClure, Maria Hordinsky, Ronda S. Farah, Song Y. Park

minoxidil topical minoxidil low-dose oral minoxidil scarring alopecia central centrifugal cicatricial alopecia frontal fibrosing alopecia lichen planopilaris traction alopecia Rogaine

TLDR Minoxidil may help with hair regrowth and disease stabilization in scarring alopecia, but side effects vary, needing more research for consistent safety and effectiveness.

The review evaluates the safety and efficacy of topical minoxidil (TM) and low-dose oral minoxidil (LDOM) in treating scarring alopecia. The study analyzed various studies on the use of TM and LDOM in central centrifugal cicatricial alopecia, frontal fibrosing alopecia, lichen planopilaris, and traction alopecia. The results showed mixed outcomes, with most participants experiencing benefits in terms of disease stabilization and hair regrowth. The treatments were generally well-tolerated, although some side effects were reported. Despite the positive indications, the variability in results and reported side effects highlight the need for further research to establish consistent efficacy and safety profiles for TM and LDOM in treating scarring alopecia.

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