Retinoids and Keratinization
March 1988
in “
International Journal of Dermatology
”
TLDR Retinoids can help treat skin disorders by improving the skin's outer layer.
The document "Retinoids and Keratinization" from 1988 reviewed the role of retinoids, derivatives of vitamin A, in the process of keratinization, which is the formation of the protective outer layer of the skin. It discussed how retinoids influenced the differentiation and proliferation of keratinocytes, the primary cell type in the epidermis, and highlighted studies showing that retinoids could modulate epidermal cell growth, enhance the production of specific keratins, and affect the structural integrity of the skin. The review underscored the potential therapeutic applications of retinoids in treating skin disorders characterized by abnormal keratinization, such as psoriasis and ichthyosis.
