Repeated finasteride administration induces depression-like behavior in adult male rats

    June 2019 in “ Behavioural Brain Research
    Rao G. Sasibhushana, B.S. Shankaranarayana Rao, B.N. Srikumar
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    TLDR Finasteride use can cause depression-like behavior in male rats.
    The study investigated the effects of repeated administration of finasteride, a drug used to treat male pattern hair loss and benign prostatic hyperplasia, on depression-like behavior in adult male rats. The study found that repeated administration of finasteride induced depression-like behavior in rats, as evidenced by increased immobility time and decreased grooming duration. The study suggests that short-term finasteride administration itself may result in depression-like behavior. The study highlights the need for further research in this area.
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