Refractory Dermatophytosis in a Spitz Dog Successfully Managed with Posaconazole: A Case Report

This case report details the successful management of refractory dermatophytosis in an 8-year-old Spitz dog using posaconazole, following poor responses to standard antifungal treatments like itraconazole and topical agents. The dog presented with persistent alopecia, scaling, erythema, and pruritus. Diagnosis was confirmed through microscopic examination, culture, and punch biopsy. Antifungal susceptibility testing (AFST) guided the selection of posaconazole, leading to marked clinical improvement without adverse effects. The report underscores the diagnostic challenges of recurrent dermatophytosis and suggests that AFST-guided treatment strategies, including posaconazole, may effectively manage infections unresponsive to standard therapies.