Erythroderma, Alopecia, Anhidrosis, and Vitiligo as Complications of a Red Ink Tattoo: A Case Report

    November 2025 in “ Clinics and Practice
    Mateusz K. Mateuszczyk, Magdalena Łyko, Andrzej Bieniek, Joanna Maj, Alina Jankowska‐Konsur
    TLDR Red ink tattoos can cause severe skin reactions and complications, especially in those with autoimmune tendencies.
    This case report describes a severe reaction to a red ink tattoo in a 36-year-old Caucasian male, resulting in erythroderma, alopecia universalis, anhidrosis, and vitiligo. Despite treatments with medications like glucocorticosteroids and cyclosporine, the patient experienced persistent anhidrosis and alopecia, with only partial improvement in vitiligo. Surgical removal of the tattoo fragments led to some skin condition improvements, but normal sweating and pigmentation did not return. Histological examinations indicated a low likelihood of sweat function recovery. The report highlights the need for better regulation of tattoo ink composition and increased awareness of potential complications, especially in individuals with autoimmune predispositions. The use of baricitinib showed promise in stabilizing vitiligo and promoting hair regrowth.
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