Quaternary Ammonium Salt-Modified Isabgol (Psyllium) Scaffold as an Antibacterial Dressing for Improved Wound Healing

The study developed a novel wound dressing using quaternary ammonium salt-modified Isabgol (Psyllium) to enhance wound healing through its antibacterial and biocompatible properties. The Isabgol was chemically modified with Epoxy propyl trimethyl ammonium chloride, confirmed by 13C NMR and FTIR analysis, to provide antibacterial activity. The resulting scaffold exhibited a porous structure, excellent swelling properties, and was biodegradable, thermally, and mechanically stable. It effectively absorbed wound exudates, maintained a moist environment, and prevented infections, which are critical for healing chronic wounds. The material was also suitable for blood contact applications and offered a cost-effective solution due to the low cost of Isabgol.