Sharp Cell Type Boundaries Emerge From Coordinated Morphogen Signaling

September 2026 in “ Genes & Development ”

Ruiqi Li, Yiqun Jiang, Sarah Platt, Tianchi Xin, Shagun Lukkad, Sarah Van, Kevin A. Peterson, Ryan Driskell, Jonathan Zhu, Hainan Lam, Eva-LaRue Barber, David H. Wang, Chae Ho Lim, Makoto M. Taketo, Yuval Kluger, Peggy Myung

Studysummary This study found that Wnt and Hedgehog signaling coordinate to create sharp cell type boundaries during hair follicle development by synchronizing cell cycle exit and differentiation.

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