Pyoderma Gangrenosum With Neurofibromatosis: Understanding A Possible Relationship And Identifying Risk With Immunosuppressants

    Mihika Noronha, Vijay Aithal
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    TLDR The document suggests doctors should watch for bone marrow suppression and severe hair loss in patients treated with Azathioprine.
    The document presents a rare case of a patient with both Pyoderma Gangrenosum and Neurofibromatosis, conditions that are usually unrelated. This is only the second reported case of such an association. The patient also developed bone marrow suppression after being treated with Azathioprine, an immunosuppressant, and experienced an acute onset of Telogen Effluvium, a form of hair loss. The study emphasizes the need for medical professionals to be aware of the potential for myelosuppression (a decrease in bone marrow activity) with Azathioprine, which can present as sudden, severe hair loss.
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