Public Interest In JAK Inhibitors For Alopecia Areata: A Google Trend Analysis

April 2025

J. E. Howard, Nourine A. Kamili, Loren D. Krueger

JAK inhibitors alopecia areata hair loss FDA approval

TLDR Interest in JAK inhibitors for hair loss increased significantly after media coverage and FDA approval.

The study analyzes public interest in JAK inhibitors for alopecia areata using Google Trends data. It found a significant increase in searches for "JAK inhibitor + Hair Loss" during 2019-2020 and 2020-2021, likely due to media coverage before FDA approval. Post-approval in 2021-2022, interest in "JAK inhibitor" and "JAK inhibitor + Alopecia Areata" surged and remained high through 2023. The authors emphasize the importance of patient education on JAK-inhibitor use and recommend that physicians guide patients on appropriate treatments for hair loss disorders.

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Research cited in this study

1 / 1 results

research Baricitinib for the Treatment of Alopecia Areata

6 citations, May 2023 in “Drugs”

Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

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6 / 54 results

community So we’re just ok with taking a research chemical now?

in Treatment 177 upvotes 4 years ago

The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

community What else is good. Besides the big 3.

in Chat 35 upvotes 6 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community find a cure for this shit already

in Chat 204 upvotes 4 years ago

Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community My experience and a discourse on “DUPA”

in Chat 46 upvotes 2 years ago

How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

community I’m 14 years old and I’m losing more hair than my dad. I’ve gone to the doctor 2 times because of this and I’ve received no help. I’m starting to feel like It’s worthless and my hairs gonna look like this forever. I don’t know how anyone could help me but it’s always worth a shot.

in Treatment 4 years ago

A 14 year old who is experiencing hair loss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hair loss such as minoxidil, finasteride, RU58841 and addressing the cause of the hair loss.

Related Research

1 / 1 results

research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.