Monotherapy with Platelet-Rich Plasma for Male and Female Pattern Baldness: Protocol for a Systematic Review

July 2021

Aditya K. Gupta, Mesbah Talukder, Mary A Bamimore

platelet-rich plasma PRP male pattern baldness female pattern baldness hair density hair thickness adverse events

TLDR The document is about planning a review to assess if PRP alone is effective for treating hair loss in men and women.

This document outlines the protocol for a systematic review that aims to evaluate the effectiveness of platelet-rich plasma (PRP) as a standalone treatment for male and female pattern baldness. The review will include randomized controlled trials (RCTs) that have used PRP as a monotherapy for this condition. The primary outcome will be the change in hair density, while secondary outcomes will include changes in hair thickness, patient satisfaction, and adverse events. The review will follow the PRISMA guidelines for systematic reviews and meta-analyses. The results of this review will provide evidence-based recommendations for the use of PRP in treating pattern baldness.

View this study on inplasy.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 88 results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 8 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What else is good. Besides the big 3.

in Chat 35 upvotes 6 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Losing Hair on Dutasteride? You might have LPP

in Research/Science 94 upvotes 1 month ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 14 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 1 month ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community When are we getting a cure to hair loss?

in Chat 2 years ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

Similar Research

6 / 1000+ results

research Platelet Rich Plasma in Androgenic Alopecia in Male and Female Patients: A Myth, A Prospective Study

1 citations, May 2018 in “Journal of Evolution of medical and Dental Sciences”

Platelet Rich Plasma (PRP) injections can effectively reduce hair loss and improve hair growth in both men and women suffering from androgenic alopecia.

research Lyophilized Growth Factor Intralesional Injection in Female Pattern Hair Loss: A Clinical and Trichoscopic Study

February 2021 in “Dermatologic Therapy”

Injections improve hair growth, density, and thickness in women safely.

research Platelet-Rich Plasma for Treating Androgenic Alopecia: A Systematic Review

27 citations, June 2019 in “Aesthetic Plastic Surgery”

Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.

research Hair Loss in Men and Women: Medical and Surgical Treatments for Androgenic Alopecia

April 2019 in “Advances in Cosmetic Surgery”

The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version

145 citations, November 2017 in “Journal of The European Academy of Dermatology and Venereology”

Use minoxidil for hair loss treatment; assess results after 6 months.

research The Efficacy of Platelet-Rich Plasma in Hair Restoration and Facial Aesthetics: A Systematic Review and Meta-Analysis

31 citations, January 2019 in “Journal of Cutaneous Medicine and Surgery”

Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.