Use of Platelet-Rich Plasma in Treating a Wound Infection Following Tophi Rupture: A Case Report

This case report discusses the use of platelet-rich plasma (PRP) therapy in treating a wound infection following tophi rupture in a 34-year-old man with a long history of gout. The patient presented with a severe wound on the dorsum of his left foot, characterized by the discharge of white urate crystals and infection. Despite initial conventional treatments, the wound healing was challenging due to its size, insufficient blood supply, and inflammation. PRP therapy was administered, resulting in successful wound healing, with the wound becoming shallower, smaller, and the skin color returning to normal within 2 months. PRP's effectiveness is attributed to its ability to promote cell regeneration, restore blood circulation, and control infection. The report highlights the potential of PRP in managing chronic non-healing wounds caused by tophi, although it notes the need for further studies to establish standardized clinical indicators for assessing treatment effectiveness.