Protection Against Cytosine Arabinoside-Induced Alopecia by Minoxidil in a Rat Animal Model

July 1995 in “ International Journal of Dermatology ”

A. Hussein

minoxidil cytosine arabinoside chemotherapy-induced alopecia Rogaine

TLDR Minoxidil helps prevent hair loss from chemotherapy in rats.

In 1995, a study found that minoxidil can protect against hair loss induced by the chemotherapy drug cytosine arabinoside in a rat animal model. The researchers suggest that minoxidil may be a useful adjunct therapy for cancer patients undergoing chemotherapy to prevent hair loss. The mechanism of action of minoxidil in its protection against chemotherapy-induced alopecia is currently unknown and under investigation.

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research Quantitative Estimation of Hair Growth I. Androgenetic Alopecia in Women: Effect of Minoxidil

85 citations , December 1990 in “Journal of Investigative Dermatology”

Minoxidil promotes hair growth in women with early-stage alopecia.

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research Five-year follow-up of men with androgenetic alopecia treated with topical minoxidil

70 citations , April 1990 in “Journal of The American Academy of Dermatology”

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Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

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Minoxidil can lower blood pressure in some people.

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6 / 6 results

research Original Article: Study on the Clinical Characteristics of Chemotherapy-Induced Permanent Alopecia

December 2013 in “대한피부과학회지”

Chemotherapy can cause permanent hair loss.

research Low-Level Laser Treatment Accelerated Hair Regrowth in a Rat Model of Chemotherapy-Induced Alopecia

43 citations , June 2012 in “Lasers in Medical Science”

Low-level laser treatment helped rats regrow hair faster after chemotherapy.

research Treatment of Chemotherapy-Induced Alopecia

64 citations , July 2011 in “Dermatologic Therapy”

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.