Positive lymphocyte transformation test in a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution

    July 2005 in “ Contact Dermatitis
    Tobias Hagemann, B. Schlütter-Böhmer, Jean-Pierre Allam, Thomas Bieber, Natalija Novak
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    TLDR Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
    The study reports a case of a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution. The patient had a positive lymphocyte transformation test (LTT), which is a useful complementary read-out device in clinical practice to differentiate between allergic and irritative adverse effects and identify the causative allergen. The study suggests that patients with sensitizations against propylene glycol are candidates for preparations with alternative solvents, while patients with allergies to the active ingredient itself are no longer candidates for treatment with minoxidil and should undergo alternative therapeutic options. The paper is from 17 years ago and may be out of date.
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