Positive lymphocyte transformation test in a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution
July 2005
in “Contact Dermatitis”
TLDR Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
The study reports a case of a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution. The patient had a positive lymphocyte transformation test (LTT), which is a useful complementary read-out device in clinical practice to differentiate between allergic and irritative adverse effects and identify the causative allergen. The study suggests that patients with sensitizations against propylene glycol are candidates for preparations with alternative solvents, while patients with allergies to the active ingredient itself are no longer candidates for treatment with minoxidil and should undergo alternative therapeutic options. The paper is from 17 years ago and may be out of date.
View this study on onlinelibrary.wiley.com →
Cited in this study
research A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss
5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
research Androgenetic alopecia: pathogenesis and potential for therapy
Hair loss needs more research for better treatments.
research Allergic contact dermatitis to topical minoxidil solution: Etiology and treatment
Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
research Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment
Minoxidil increases hair weight and count temporarily in men with hair loss.
research Allergic contact dermatitis from minoxidil
Minoxidil can cause allergic reactions, but testing helps identify the cause.
Related
research Positive lymphocyte transformation test in a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution
Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.