Development of a Portable Reflectance Confocal Microscope and Its Application in the Noninvasive In Vivo Evaluation of Mesenchymal Stem Cell-Promoted Cutaneous Wound Healing

December 2022 in “ Bio-Design and Manufacturing ”

Lixing Zhang, Xin Miao, Meijia Wang, Aihua Shi, Jingwen Wang, Zhonglin Ma, Yunhai Zhang, Jingzhong Zhang, Shuang Yu

reflectance confocal microscope mesenchymal stem cells cutaneous wound healing collagen bundle formation re-epithelization hair follicle regeneration

Studysummary This study demonstrates that the newly developed portable reflectance confocal microscope (PRCM) offers real-time, noninvasive monitoring of wound healing processes by visualizing skin morphology in both mice and humans.

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research Wound Healing: Cellular Mechanisms and Pathological Outcomes

1425 citations , September 2020 in “Open Biology”

This review explores the cellular mechanisms of tissue repair and discusses how advancements in understanding wound pathology could lead to the development of more effective therapies for chronic, non-healing wounds, which are prevalent among individuals with diabetes and aging.