Polycystic Ovary Syndrome: Conditions, Genetics, and Current Treatments

    November 2016 in “ Endocrinology&Metabolism International Journal ”
    Imteyaz Qamar
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    TLDR PCOS has no cure, but treatments can manage symptoms and improve health.
    Polycystic ovary syndrome (PCOS) was a common endocrine disorder affecting 7-10% of women of reproductive age and was a leading cause of female infertility. It was characterized by polycystic ovaries, hyperandrogenism, and anovulation, and was associated with conditions like obesity, type 2 diabetes, insulin resistance, and cardiovascular disease. Insulin resistance was a key pathophysiological feature, and dyslipidemia was common in affected women. Despite extensive research, the exact cause of PCOS remained unclear, though it was thought to involve an internal ovarian abnormality. There was no medicinal cure for PCOS, but treatments such as oral contraceptive pills, anti-androgens, and metformin could help manage symptoms and improve menstrual regularity and metabolic conditions. The review discussed the conditions, genetic factors, current treatments, and future perspectives related to PCOS.
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