Pattern Hair Loss Distribution: A Novel Presentation For Alopecia Areata
April 2023
in “
Journal of Dermatological Treatment
”
Studysummary This study observed a significant reduction in the number of hair follicles with a high proportion in catagen or telogen phase, along with visible vertical columns of connective tissue in the histopathologic examination.
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This case report discusses a 17-year-old patient with a novel presentation of alopecia areata (AA) that mimics androgenic alopecia (AGA). Despite a family history of AA and a 6-year history of diffuse hair loss, the patient showed a unique 'U' pattern hair loss and did not respond to minoxidil treatment. However, significant hair regrowth was observed after 3 months of treatment with tofacitinib, a Janus kinase (JAK) inhibitor, supporting the diagnosis of AA. The report highlights the potential for JAK inhibitors in treating AA with pattern hair loss and suggests further studies to explore this clinical phenotype.
