TLDR Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
Minoxidil treatment in dogs can cause cardiovascular damage, including arterial injury, hemorrhagic lesions, and necrosis. The study highlights the potential risks associated with minoxidil use. Minoxidil use in dogs leads to cardiovascular damage that worsens with continued use, and ß-blockers are not effective in preventing this damage. The use of minoxidil in dogs leads to three cardiovascular alterations that are caused by the active metabolite of minoxidil, not histaminic agents or sympathectomy. Minoxidil use in dogs can lead to irreversible cardiovascular damage, causing hemorrhagic lesions on the right side of the heart. The study cautions against the use of high doses of minoxidil in dogs due to the risk of cardiovascular lesions.
Cited in this study
9 / 9 results
28 citations
,
January 1989 in “Toxicologic Pathology” Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
39 citations
,
November 1984 in “Journal of Cardiovascular Pharmacology” Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
27 citations
,
August 1984 in “Experimental and Molecular Pathology” 96 citations
,
October 1981 in “Drugs” Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
35 citations
,
July 1981 in “Clinical Pharmacology & Therapeutics” Minoxidil can cause dangerous fluid buildup around the heart.
35 citations
,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
52 citations
,
March 1979 in “Toxicology and Applied Pharmacology” Minoxidil can cause heart muscle damage in dogs.
43 citations
,
January 1977 in “Toxicology and Applied Pharmacology” Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.
180 citations
,
July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.