Genetic Factors in the Etiology of Intervertebral Disc Herniation and Protrusion
May 2024
in “
International journal of medicine and psychology.
”
Studysummary This study examines the significant role genetic factors play in the development of intervertebral disc herniation and protrusion and explores how advancements in molecular genetics and translational medicine might improve diagnosis, prevention, and treatment, ultimately aiming to enhance patient outcomes and quality of life.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Intervertebral disc herniation and protrusion are common degenerative spine disorders that significantly reduce patients' quality of life. This study analyzes the role of genetic factors in these conditions, identifying key candidate genes, polymorphisms, and mutations linked to increased risk, along with epigenetic mechanisms affecting gene expression. It highlights the interaction between genetic and non-genetic factors in the disease's development. The research underscores the potential of molecular genetics and translational medicine to enhance diagnosis, prevention, and treatment strategies, emphasizing that genetic factors are crucial in the pathology's development and offer promising avenues for improving patient outcomes.
