Reactions and Side Effects of Ovulation Inhibitors on the Skin
January 1978
in “
PubMed
”
oral contraceptive estrogen melanin-stimulating hormone sebum production chlormadinon acetate antiandrogenic effect androgenetic alopecia nortestosterone peroral dermatitis lupus erythematosus porphyria cutanea tarda liver dysfunction vaginal candidosis herpes gestationes trichomoniasis candida mycosis Ovosiston
Studysummary This study reviewed various dermatological conditions associated with oral contraceptive use, highlighting increased pigmentation, decreased sebum production, and changes in hair growth, among other effects. Our plain-language summary of this paper — not a Tressless recommendation.
The document provided an overview of dermatological diseases associated with oral contraceptive (o.c.) use. It was found that o.c. use could lead to increased pigmentation due to elevated melanin-stimulating hormone production, decreased sebum production beneficial for acne, and disturbances in hair growth balance. Androgenetic alopecia was linked to preparations containing nortestosterone. Other observed conditions included peroral dermatitis, lupus erythematodes visceralis, allergic skin reactions, and porphyria cutanea tarda, often related to liver dysfunctions. Vaginal candidosis and herpes gestationes were also more frequent among o.c. users. The study involved 166 patients, noting that acne vulgaris improved more frequently among Ovosiston users, and liver damage was confirmed in all cases of porphyria cutanea tarda.
