Thyroid Peroxidase Antibodies in Patients with Telogen Effluvium

February 2010 in “ Journal of the European Academy of Dermatology and Venereology ”

Manuela Baldari, Marcella Guarrera, Alfredo Rebora

thyroid peroxidase antibodies TPO-Ab telogen effluvium TE androgenetic alopecia AGA alopecia areata AA autoimmune component thyroid antibodies chronic hair shedding pattern hair loss autoimmune hair loss

Studysummary Some people with chronic hair loss may have thyroid autoimmunity.

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The document reported on two studies, with the first study revealing that thyroid peroxidase antibodies (TPO-Ab) were present in 24.1% of 97 patients with chronic telogen effluvium (TE) and TE + androgenetic alopecia (AGA), suggesting an autoimmune component in the pathogenesis of TE. This prevalence was notably higher in women at 29%. The control group, consisting of 36 individuals with alopecia areata (AA), showed a 38.9% prevalence of TPO-Ab. The second study was unrelated to hair loss and detailed a case of a 70-year-old man with a scalp lesion that was a collision tumor of pigmented basal cell carcinoma and melanoma, diagnosed through dermoscopic features.

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research Trichodynia Is a Distinguishing Symptom of Telogen Effluvium

24 citations , March 2009 in “Journal of the European Academy of Dermatology and Venereology”

This paper highlights trichodynia as a distinguishing symptom of telogen effluvium, but it does not present new clinical findings.

research Distinguishing Androgenetic Alopecia From Chronic Telogen Effluvium When Associated in the Same Patient

63 citations , October 2005 in “Archives of Dermatology”

This study reports that a hair shedding threshold of 100 hairs or more may provide the best concordance with clinical diagnosis for distinguishing chronic telogen effluvium from androgenetic alopecia.

research Management of Hair Loss in Women

29 citations , January 1993 in “Dermatologic Clinics”

This paper reviews diffuse androgen-dependent alopecia and chronic telogen effluvium in women, highlighting diagnostic challenges and management issues, but reports no new clinical findings; the authors suggest effective treatments are available.