The Impact of COVID-19 on the Menstrual Cycle: A General Perspective

    March 2023 in “ Brazilian Journal of Health Review ”
    Anna Caroline Loyola Sampaio, Jéssica dos Santos Coelho, Paloma Luna Maranhão Conrado, Valda Lúcia Moreira Luna, Pauliana Valeria Machado Galvão, George Alessandro Maranhão Conrado
    TLDR The combination tablet of finasteride and doxazosin works the same as taking each drug separately.
    The study aimed to evaluate the pharmacokinetic profile and bioequivalence of a fixed combination tablet containing finasteride (5 mg) and doxazosin (2 mg) compared to the individual administration of these drugs. Conducted as a randomized, crossover study with 30 subjects, the results showed no significant differences in the pharmacokinetic parameters (AUC0-72h, AUC0-∞, and Cmax) between the combination tablet and the single agents. The mean ratios of AUC0-72h/AUC0-∞ for finasteride and doxazosin were nearly 100%, indicating adequate sampling time and confirming bioequivalence. This suggests that the combination tablet does not alter the pharmacokinetics of the individual drugs, supporting its use in clinical practice.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 2 years ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community Warning: Minoxidil usage around pets

      in Minoxidil  454 upvotes 10 months ago
      Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

      community Misapplication of topical finasteride/minoxidil?

      in Finasteride  98 upvotes 4 days ago
      The user experienced hairline recession despite using topical finasteride/minoxidil and is considering whether misapplication was the cause. They are exploring options after experiencing side effects from oral finasteride, including possibly returning to the topical formulation with adjusted application methods.

      community Should I use topical min + fin at 16 even if my dermatologist approved?

      in Finasteride  86 upvotes 2 weeks ago
      A dermatologist prescribed a 16-year-old a mix of 5% topical minoxidil and 0.1% topical finasteride for hair loss, but the user is concerned about side effects. Another user advises against using finasteride at a young age due to potential growth impacts and suggests consulting a doctor to assess growth completion.

    Related Research

    1 / 1 results