New advances in the treatment of thin endometrium

Thin endometrium (TE), defined as a mid-luteal endometrial thickness of ≤7mm, can lead to lower embryo implantation and clinical pregnancy rates, affecting outcomes from assisted reproductive treatments. The causes of TE include hormonal influences, uterine cavity factors, long-term contraceptive use, and ovulation-promoting drugs, with some cases having unknown etiology. Current treatments involve pharmacological methods, regenerative medicine, intrauterine infusions, and complementary therapies, though their mechanisms are not fully understood. Researchers are exploring new approaches to improve TE treatment outcomes, aiming to enhance endometrial tolerance and increase embryo implantation rates, thereby assisting more couples facing infertility.