Nevus comedonicus syndrome: a case associated with multiple basal cell carcinomas and a rudimentary toe

    June 2005 in “ International Journal of Dermatology ”
    Erkan Alpsoy, Çiçek Durusoy, Gülay Özbilim, Gülten Karpuzoğlu, Ertan Yılmaz
    TLDR A man with nevus comedonicus syndrome had multiple skin issues, including basal cell carcinomas, which improved with treatment.
    A 28-year-old man with nevus comedonicus syndrome presented with widespread black spots, cysts, and a rudimentary toe. He developed pigmented basal cell carcinomas (BCCs) on his neck and chest, alongside recurrent abscesses and cysts. Dermatologic examination showed dilated follicular orifices with keratinous material, erythematous papules, nodules, cysts, and scars. Histopathology confirmed multiple BCCs adjacent to nevus comedonicus. Treatment included antibiotics, topical tretinoin, benzoyl peroxide, cryosurgery, and surgical removal of larger BCCs and cysts, resulting in some improvement. The patient remained under observation and in good health.
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