Navigating Rhupus Complexity

    January 2024 in “ Ankara City Hospital Medical Journal ”
    Dilara Bulut Gökten, Rıdvan Mercan
    TLDR Rhupus is a complex syndrome that combines rheumatoid arthritis and lupus, making diagnosis challenging.
    Rhupus is a rare syndrome characterized by the overlap of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), with only about 60 cases documented in the literature. This case study discusses a 42-year-old female patient with Rhupus who exhibited symptoms such as inflammatory arthritis, bilateral wrist swelling, severe malar rash, oral ulcers, alopecia, anemia, and thrombocytopenia. Her laboratory results showed elevated erythrocyte sedimentation rate and decreased hemoglobin and platelet count. The case highlights the diagnostic challenges due to the lack of well-defined clinical criteria and aims to contribute to the understanding of this complex syndrome.
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